骨巨细胞瘤多发生在20～40岁青壮年人的长骨骨端。发生在小儿骨干虽有报道,但很少见。我们近30年收治的骨巨细胞瘤的病例中,有4例发生在14岁以下小儿。其中3例为干骺端巨细胞瘤,报告如下: 例1,男,13岁。因跌倒左髋部着地后,局部肿痛而入院,经拍X线片发现左股骨颈部及转子间部位有破坏,呈肥皂泡沫样改变,并有骨折。临床诊断为左股骨颈巨细胞瘤,病理骨折。入院1周后手术。术中冰冻切片快速活检:软骨母细胞瘤可能性较大。行肿瘤刮除植自家髂骨,术后病理:基质正常,可见大量巨细胞,报告为巨细胞肿瘤Ⅰ级。15年随访,无复发,功能基本正常,能参加一般农业劳动。 Giant cell tumors of the bones occur at the long bones of young adults aged 20 to 40 years. Although it has been reported in children’s backbones, it is rare. Of the cases of giant cell tumor of bone that we treated in the past 30 years, 4 cases occurred in children under 14 years of age. Three of them were metaphyseal giant cell tumors. The report is as follows: Example 1, male, 13 years old. After falling down on the left hip, he was admitted to the hospital with localized swelling and pain. After the X-ray film was taken, the left femur neck and the intertrochanter site were found to be damaged, showing soap bubble-like changes and fractures. Clinical diagnosis is left giant femoral neck tumor, pathological fractures. One week after admission, the operation was performed. Intraoperative frozen section biopsy: Chondroblastoma is more likely. The tumors were scraped off from the iliac bones of the house. Postoperative pathology: The stroma was normal and a large number of giant cells were seen. The giant cell tumor was reported as grade I. After 15 years of follow-up, there was no recurrence and the function was basically normal. They could participate in general agricultural labor.