感染性休克以感染为病因,微循环障碍和细胞损伤为特征,病死率高(30～60%),是休克综合征的严重类型.感染性休克常由全身或严重局部感染引起.常见的病原体为格兰氏阴性菌(如脑膜炎双球菌、痢疾杆菌、变形杆菌等),主要以内毒素致病;其次为格兰氏阳性菌(如链球菌、金葡菌、白喉杆菌等),主要以外毒素致病;此外,尚有病毒、立克次体、支原体和霉菌、原虫等。某些原发病和易使宿主免疫性受损的因 Septic shock is characterized by an etiology of infection, microcirculation and cell damage, with a high case-fatality rate (30-60%) and is a severe type of shock syndrome. Septic shock is often caused by systemic or severe local infection. Common pathogens Gram-negative bacteria (such as meningococcus, Shigella, Proteus, etc.), mainly to endotoxin pathogenic; followed by Gram-positive bacteria (such as Streptococcus, Staphylococcus aureus, diphtheria bacilli, etc.), mainly outside Toxins pathogenic; In addition, there are viruses, rickettsia, mycoplasma and mold, protozoa and so on. Some of the primary disease and susceptibility to host immune damage