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目的探讨Ⅰ类切口手术围术期抗菌药物使用专项整治措施及成效。方法回顾性抽取整治前、整治初期和整治中期的Ⅰ类切口手术病历共807份,根据《抗菌药物临床应用指导原则》统计分析Ⅰ类切口手术围术期抗菌药物使用情况。结果专项整治后Ⅰ类切口手术围术期抗菌药物使用率由97.8%下降至12.9%(χ2=128.99,P=0.00),术前30 min~2 h抗菌药物使用率由5.6%上升至90.9%(χ2=55.86,P=0.00),抗菌药物二联使用率下降至0,抗菌药物使用时间控制在24 h内比例由整治前的3.4%上升至27.2%,差异有统计学意义(χ2=9.91,P=0.002)。但抗菌药物使用费用未达到理想的整治效果,差异无统计学意义(t=0.1545,P>0.05)。结论Ⅰ类切口手术围术期抗菌药物使用整治效果显著,但需继续加强监管,巩固整治成效。
Objective To discuss the special treatment measures and results of antimicrobial agents used in perioperative period of type Ⅰ incision. Methods A total of 807 cases of type Ⅰ incisional surgery before remediation, early remediation and mid-remediation were retrospectively collected. According to the Guiding Principles of Clinical Application of Antibacterials, the usage of antibacterials during the perioperative period was analyzed statistically. Results The rate of antibacterials utilization decreased from 97.8% to 121.9% (χ2 = 128.99, P = 0.00) during the perioperative period after special revisions, and the antibacterial drug usage increased from 5.6% to 90.9% (χ2 = 55.86, P = 0.00), the use of antibacterials in combination decreased to 0, and the proportion of antibacterials used within 24 h increased from 3.4% before remission to 27.2% with a statistically significant difference (χ2 = 9.91 , P = 0.002). However, the cost of antibacterial drugs did not achieve the desired remission effect, the difference was not statistically significant (t = 0.1545, P> 0.05). Conclusions The perioperative management of antimicrobial agents in class Ⅰ incision is significant. However, it is necessary to continue to strengthen supervision and consolidate the effectiveness of remediation.