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1文献来源Webb AJS,Fischer U,Mehta Z,et al.Effects of antihypertensive-drug class on interindividual variation in blood pressure and risk of stroke:Asystematic review and meta-analysis[J].Lancet,2010,375(9718):906-915.2证据水平1a。3背景血压是心血管事件的强力预测因子,收缩压>115mmHg占到了卒中人群归因危险度的60%以上[1],在40～69岁的人群中,收缩压增高20mmHg会使患卒中的风险倍增[2]。在随机对照试验(randomised controlled trial,RCT)中,平
1 References Webb AJS, Fischer U, Mehta Z, et al. Effects of antihypertensive-drug class on interindividual variation in blood pressure and risk of stroke: Asystematic review and meta-analysis [J]. Lancet, 2010, 375 (9718) : 906-915.2 Level of Evidence 1a. Background Blood pressure is a strong predictor of cardiovascular events with systolic blood pressure> 115 mm Hg accounting for more than 60% of the at-risk for stroke population [1]. Increasing systolic blood pressure by 20 mm Hg in 40-69 years of age causes stroke Double the risk [2]. In a randomized controlled trial (RCT), flat