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目的:研究与分析糖尿病肾病患者红细胞免疫及抗氧化状态相关指标的变化情况。方法:将2015年1月~2016年6月期间于本院进行治疗的66例糖尿病肾病患者设为观察组,同时将66名同龄健康人设为对照组。检测与比较两组同龄者的红细胞免疫及抗氧化状态相关指标,同时比较不同糖尿病肾病分期患者的红细胞免疫及抗氧化状态相关指标水平。结果:观察组的红细胞免疫及抗氧化状态相关指标明显差于对照组,且不同糖尿病肾病分期患者的检测水平也呈现明显差异,P均<0.05,检测水平之间均存在显著性差异。结论:糖尿病肾病患者红细胞免疫及抗氧化状态相关指标明显较差,糖尿病分期较高者的检测结果也相对较差,因此应注意对糖尿病肾病患者进行上述方面的改善。
Objective: To study and analyze the changes of erythrocyte immune and antioxidant status in patients with diabetic nephropathy. Methods: Sixty-six patients with diabetic nephropathy treated in our hospital from January 2015 to June 2016 were enrolled as observation group and 66 healthy subjects of same age as control group. The indexes of erythrocyte immunity and antioxidant status of the same age group were detected and compared. The levels of erythrocyte immune and antioxidant status in different stages of diabetic nephropathy were also compared. Results: The indexes related to erythrocyte immunity and antioxidant status in the observation group were significantly lower than those in the control group. There were also significant differences in the detection levels of patients with different stages of diabetic nephropathy (P <0.05). There was a significant difference between the two groups. Conclusion: The index of erythrocyte immunity and anti-oxidation status in patients with diabetic nephropathy is significantly poor, and the test results of the patients with higher diabetes stage are also relatively poor. Therefore, we should pay attention to the above-mentioned improvement in patients with diabetic nephropathy.