Characterisation and understanding of the stressestrainepermeability behaviour of a clay host rock during damage and recompaction are essential for prediction of excavation damaged zone and for assessment of its impact on the repository safety. This important issue has been experimentally studied in triaxial compression tests on the Callovo-Oxfordian clay rock in this study. The samples were sequentially loaded by(1) hydrostatic precompaction to close up sampling-induced microcracks,(2)applying deviatoric stresses to determine damage and permeability changes, and(3) recompression along different loading paths to examine reversibility of the damage. The critical stress conditions at the onset of dilatancy, permeability percolation, failure strength, and residual strength are determined. An empirical model is established for fracturing-induced permeability by considering the effects of connectivity and conductivity of microcracks. The cubic law is validated for the variation of permeability of connected fractures with closure. The experiments and results are also presented and discussed. Characterization and understanding of the stressestrainepermeability behavior of a clay host rock during damage and recompaction are essential for prediction of excavation damaged zone and for assessment of its impact on the repository safety. This important issue has been experimentally studied in triaxial compression tests on the Callovo- Oxfordian clay rock in this study. The samples were sequentially loaded by (1) hydrostatic precompaction to close up sampling-induced microcracks, (2) applying deviatoric stresses to determine damage and permeability changes, and (3) recompression along different loading paths to examine reversibility of the damage. The critical stress conditions at the onset of dilatancy, permeability percolation, failure strength, and residual strength are determined. An empirical model is established for fracturing-induced permeability by considering the effects of connectivity and conductivity of microcracks. The cubic law is validated for the variation of permeabil ity of connected fractures with closure. The experiments and results are also presented and discussed.