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慢性阻塞性肺疾病急性加重(AECOPD)指呼吸道症状加重超出每天的日常变异范围,需要改变基础治疗用药,往往为急性发病。气道慢性炎症受各种因素(感染、非感染)触发使炎症反应加剧,均可引起病情加重。引起支气管黏膜水肿、黏液分泌增多、平滑肌收缩、气流受限加剧、动态过度充气及相关临床表现,并可引起全身性炎症反应,
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) refers to the exacerbation of respiratory symptoms beyond the daily variability of the day and requires changes in therapies for basic treatment, often acute. Chronic airway inflammation by a variety of factors (infection, non-infection) trigger the inflammatory response, can cause illness worse. Causing bronchial mucosal edema, increased mucus secretion, smooth muscle contraction, increased airflow limitation, dynamic hyperventilation and related clinical manifestations, and can cause systemic inflammatory response,