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目的气道闭合压(P0.1)、呼出气末二氧化碳(PetCO2)在小儿非肺源性呼吸衰竭机械通气中的临床价值研究报道甚少。为此,该研究在这方面做一探讨。方法对于收住儿童ICU的呼吸衰竭机械通气的患儿,监测P0.1,PetCO2。结果P0.1在成功撤机时与上呼吸机第1天比较差异均有显著性,各年龄组0岁～,1岁～,3～16岁数据依次如下:1.8±0.25cmH2O,2.0±0.27cmH2O,2.1±0.28cmH2O。呼出气末二氧化碳(PetCO2)与动脉血二氧化碳(PaCO2)有显著正相关(r=0.894,P<0.001)。结论在机械通气中,通过检测P0.1,PetCO2的动态变化,可了解患者的病情变化,指导呼吸机参数的调节;为临床小儿呼吸机的成功撤离提供了有关肺功能的预测指标。
The clinical value of the purpose of the airway closure pressure (P0.1), exhaled end-capped carbon dioxide (PetCO2) in pediatric non-pulmonary respiratory failure mechanical ventilation is poorly reported. To this end, the study made a discussion in this regard. Methods For children with mechanically ventilated respiratory failure who were admitted to the ICU, P0.1 and PetCO2 were monitored. Results P0.1 was significantly different from the first day of ventilator when weaning was successful. The data of 0 ~ 1 year old and 3 ~ 16 years old in each age group were as follows: 1.8 ± 0.25cmH2O, 2.0 ± 0.27 cmH2O, 2.1 ± 0.28 cmH2O. There was a significant positive correlation between PetCO2 and PaCO2 (r = 0.894, P <0.001). Conclusion During the mechanical ventilation, the dynamic changes of P0.1 and PetCO2 can be used to understand the changes of patients’ condition and guide the adjustment of ventilator parameters. The prediction of lung function can be provided for the successful withdrawal of clinical pediatric ventilator.