儿童疾病临床过程有一定特殊性,尤其是危重患儿早期症状和体征不明显,且病情进展迅速,往往在实验室指标尚未出现阳性结果时病情已恶化。降钙素原(procalcitonin,PCT)作为一种新的在严重感染、手术后评估等方面的早期诊断指标在国外已广泛应用于SICU,且临床评价良好。本文就PCT的生理特征、在儿科危重症与手术评估中的应用进展作一综述。 Clinical manifestations of childhood diseases have some particularities. In particular, the early symptoms and signs of critically ill children are not obvious, and the disease progresses rapidly, often when the laboratory indicators have not yet appeared positive results have deteriorated. Procalcitonin (PCT) has been widely used in SICU as a new early diagnostic indicator in severe infection and postoperative evaluation, and its clinical evaluation is good. This article reviews the physiological characteristics of the PCT and its application in the evaluation of pediatric critical illness and surgery.