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目的:分析国内外关于重型新型冠状病毒肺炎(新冠肺炎)的研究热点及研究前沿。方法:用CiteSpace软件分别对中国知网(CNKI)及科学网(Web of Science)两个数据库2020年1月30日至4月20日发表的重型新冠肺炎相关研究进行可视化分析,分析内容包括文献的作者、发文机构、高频关键词等。结果:共纳入389篇中文文献及59篇英文文献。用CiteSpace软件分析显示,目前国内主要有4个比较大的团队关注重型新冠肺炎相关研究,各团队内部合著较紧密,但团队之间合作欠佳;发文机构以高等院校附属医院为主,高等院校及企业参与较少。英文发文作者主要有5个研究团队,部分有合著关系;英文发文量最多的国家为中国,其次是美国、加拿大。中文关键词共现、聚类及突现词分析显示,新冠肺炎主要研究领域包括临床特征、中医药治疗、医学影像学、中西医结合治疗等;核酸检测、临床特点及临床诊断,瘟疫理论及病因机制、中医药及中西医结合治疗、重型新冠肺炎合并糖尿病及预后研究将成为今后的研究趋势,词聚类分析新冠肺炎、合并慢性基础疾病、CT影像学特征也将成为该领域研究的新趋势。英文文献关键词共现分析显示,新冠肺炎主要研究领域包括新型冠状病毒名称、疾病大流行、传染性疾病、医疗物资分配、心肌损害相关指标等。结论:国内外研究者对新冠肺炎的关注点并不完全相同,国内以研究重症临床诊断及治疗为主,国外则重视疫情应对及预防。“,”Objective:To analyze the research hotspot and frontier of severe coronavirus disease 2019 (COVID-19) in China and abroad.Methods:The CiteSpace software was used to visually analyze the relevant research of severe COVID-19 published by CNKI and Web of Science databases from January 30th to April 20th in 2020. The analysis content included the author of the literature, the publishing institutions, and high-frequency keywords.Results:There were 389 Chinese literatures and 59 English literatures included. Analysis using CiteSpace software showed that there were four large teams in China currently concerning about the research on severe COVID-19. The co-authoring of each team was relatively close, but the teams were lack of cooperation. The main issuing institutions were affiliated hospitals of colleges and universities, but colleges and enterprises had less participation. The authors of English-language publications mainly had five research teams, some of whom had co-authored relationships. The country with the most enormous volume of English-language publications was China, followed by the United States and Canada. The Chinese keyword co-occurrence, clustering and highlighted words analysis showed that the main research areas of severe COVID-19 included clinical features, traditional Chinese medicine treatment, medical imaging, integrated traditional Chinese and Western medicine treatment and so on; nucleic acid detection, clinical features and diagnosis, plague theory and etiology mechanism, traditional Chinese medicine and integrated Chinese and Western medicine treatment, severe COVID-19 combined with diabetes and prognosis research will become future research trends; keyword cluster analysis showed that severe COVID-19, combined chronic underlying diseases, CT imaging characteristics will also become new trends in the field of research. Co-occurrence analysis of keywords in English literatures showed that the main research areas of severe COVID-19 included the names of novel coronavirus, pandemic diseases, infectious diseases, medical supplies distribution, and indicators related to myocardial damage.Conclusions:Researchers in China and abroad have different concerns about severe COVID-19. Domestic research focuses on the diagnosis and treatment of severe cases, while foreign countries attach importance to epidemic response and prevention.