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本文从调理脾胃临床药效学研究着手，探索中药临床药理研究方法。以消化性溃疡为研究对象，用补中益气丸、金佛止痛丸、溃疡宁胶囊三方为主进行病灶指标、证指标、证微观定量指标的研究。结果表明：中药临床药理研究，一方面须抓住病灶指标，病灶指标是中药药效评价的基础；一方面着重于证指标，同时结合证微观定量指标的变化。三方面综合，宏观与微观相结合，分析与综合相结合，可更全面地进行中药临床药理研究。
This article starts with the study of clinical pharmacodynamics of spleen and stomach, and explores the clinical pharmacological research methods of traditional Chinese medicine. Taking peptic ulcer as the research object, using Buzhong Yiqi Pills, Jinfu Zhitong Pills and Funing Ning Capsules as the main subjects to study the lesion index, the syndrome index, and the quantitative index of the microscopic evidence. The results showed that: on the one hand, the clinical pharmacology research of traditional Chinese medicine must catch the lesion index, and the lesion index is the basis of the evaluation on the efficacy of traditional Chinese medicine; on the one hand, it focuses on the index of the syndrome, and at the same time, it combines the changes of the microscopic quantitative index. The three aspects of integration, macro and micro integration, analysis and integration can be more comprehensive clinical drug pharmacology research.