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免疫调节紊乱使得自身免疫性疾病频发免疫性血栓,进而损伤重要脏器功能,甚至导致死亡,从而增加了临床治疗的复杂性。且免疫性血栓与炎症反应呈高度相关性,免疫性炎症反应不仅可以直接损伤血管内皮细胞,促进凝血反应,还能诱导凝血系统表达炎性因子,从而扩大炎症反应和增强凝血过程,所以炎症反应越严重,凝血系统就越活跃。因炎性因子对免疫性血栓的形成影响明显,故以此为靶点进行干细胞治疗可能会成为新的临床治疗方法。
Immune regulation disorders make autoimmune diseases frequent immune thrombosis, and then damage the function of important organs, and even lead to death, thus increasing the complexity of clinical treatment. Immune thrombus and inflammatory reaction are highly correlated. Immune inflammatory reaction can not only directly damage vascular endothelial cells, promote coagulation reaction, but also induce inflammatory factors in the coagulation system to expand the inflammatory response and enhance the coagulation process, so the inflammatory response The more severe, the more active the coagulation system. Due to inflammatory factors on the formation of immune thrombus obvious impact, so as a target for stem cell therapy may become a new clinical treatment.