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目的:探讨下颌骨骨折行坚固内固定术后与感染相关的危险因素。方法:设计病例对照研究,收集我院2009年1月—2015年12月期间下颌骨骨折坚固内固定手术患者447例,其中出现术后感染的病例为26例(实验组)。从每例发生术后感染的患者入院前2周内,随机选取1例下颌骨骨折坚强内固定术后无任何并发症的患者纳入对照组,共26例。收集整理相关的变量数据,采用SAS9.2软件包在2组间行二变量和多因素Logistic回归分析,确定与术后感染相关的因素。结果:回归分析结果显示,增长的下颌骨骨折严重程度评分(OR=2.509,95% CI为1.083~5.814)以及患者欠佳的全身健康状态(OR=5.019,95% CI为1.294~19.472)是导致术后感染的相关危险因素。在二变量检验中,抗生素使用天数与术后感染具有相关性(P<0.05)。结论:骨折的严重程度和患者欠佳的身体健康状态是下颌骨骨折术后感染的危险因素。
Objective: To investigate the infection-related risk factors of mandibular fracture after rigid internal fixation. Methods: A case-control study was designed to collect 447 cases of patients undergoing rigid internal fixation for mandibular fracture in our hospital from January 2009 to December 2015, including 26 cases of postoperative infection (experimental group). A total of 26 patients were randomly assigned to control group without any complication after mandibular fracture fixation within 2 weeks before admission. Collected data related to the consolidation of variables, using SAS9.2 package 2 between the two groups and multivariate Logistic regression analysis to determine the factors associated with postoperative infection. Results: The results of regression analysis showed that the increased severity of mandibular fracture (OR = 2.509, 95% CI 1.083-5.814) and poor general health (OR = 5.019, 95% CI 1.294-19.472) Related risk factors leading to postoperative infection. In the two-variable test, the number of antibiotic days was correlated with postoperative infection (P <0.05). CONCLUSIONS: The severity of fractures and poor patient health are risk factors for postoperative mandibular fracture surgery.