论文部分内容阅读
目的:探讨新生儿胎粪吸入综合征心肌酶谱分析及意义。方法:选取2011年2月至2016年3月河南科技大学附属三门峡市中心医院新生儿胎粪吸入综合征的患儿,共计100例,为研究组。选择同期本院健康新生儿作为对照组,共计100例。对比两组出生后48 h心电图结果、心肌肌钙蛋白I及肌酸激酶同工酶(CK–MB)水平。根据研究组是否发生呼吸衰竭,进一步分为呼吸衰竭组和未发生呼吸衰竭组,分析两组心肌肌钙蛋白I及CK–MB水平。结果:两组新生儿出生后48 h心电图结果比较,差异具有统计学意义(P<0.05)。两组新生儿心肌肌钙蛋白I及CK–MB水平比较,差异具有统计学意义(P<0.05)。呼吸衰竭组和未发生呼吸衰竭组心肌肌钙蛋白I及CK–MB水平比较,差异具有统计学意义(P<0.05)。结论:测定胎粪吸入综合征新生儿的心肌酶谱可以早期发现心肌损害,帮助临床医生判断患儿病情严重程度。
Objective: To investigate the myocardial enzyme profiles of neonatal meconium aspiration syndrome and its significance. Methods: A total of 100 children with meconium aspiration syndrome from Sanmenxia Central Hospital affiliated to Henan University of Science and Technology from February 2011 to March 2016 were selected as the research group. Select the same period of hospital healthy newborn as a control group, a total of 100 cases. The 48 h electrocardiogram results, cardiac troponin I and creatine kinase MB (CK-MB) levels were compared between the two groups. According to the research group whether respiratory failure occurred, further divided into respiratory failure group and no respiratory failure group, cardiac troponin I and CK-MB levels were analyzed. Results: There was significant difference between the two groups in 48 h electrocardiogram after birth (P <0.05). The difference of cardiac troponin I and CK-MB levels between the two groups was statistically significant (P <0.05). Respiratory failure group and no respiratory failure group cardiac troponin I and CK-MB levels, the difference was statistically significant (P <0.05). Conclusion: Myocardial enzymes of neonates with meconium aspiration syndrome can detect myocardial damage early and help clinicians to determine the severity of the illness.