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肿瘤热疗(hyperthermia)是通过多种方式提高人体中的恶性组织细胞的温度并维持一定时间,导致癌细胞功能不可逆损伤或增加细胞对药物的敏感性,从而加速癌细胞的凋亡或死亡[1~3]。我们在前期研究中发现,温热刺激K562细胞可增高细胞热休克蛋白和胱天蛋白酶(caspase)-3的表达,提示温热刺激可能诱导K562细胞凋亡[4,5]。而温热刺激bcr/abl融合基因阳性的慢性粒细胞白血病(chronic myeloid
Hyperthermia is the process of accelerating the apoptosis or death of cancer cells by increasing the temperature of malignant tissue cells in the human body in a variety of ways for a certain period of time, leading to the irreversible damage of cancer cells or increasing the sensitivity of cells to drugs [ 1 ~ 3]. In our previous study, we found that warm stimulation of K562 cells can increase the expression of heat shock proteins and caspase-3, suggesting that warm stimulation may induce apoptosis in K562 cells [4,5]. The warm bcr / abl fusion gene-positive chronic myeloid leukemia (chronic myeloid