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目的:观察高强度聚焦超声(High intensity focused ultrasound)治疗子宫腺肌症的疗效和安全性。方法:对68例子宫腺肌症患者进行HIFU治疗,随访6个月,比较治疗前及治疗后6个月临床症状、实验室检查指标、超声图像的变化。结果:HIFU治疗前后子宫腺肌症病灶体积分别为(15.13±5.9)cm~3和(10.62±3.12)cm~3,痛经程度评分分别为(2.35±1.14)分和(0.92±0.77)分,血红蛋白浓度分别为(89.63±7.25)g/L和(101.47±6.87)g/L,(P<0.01)差异均有统计学意义。HIFU治疗后月经异常、痛经、下腹坠胀、膀胱压迫等临床症状明显缓解,无严重临床不良反应及并发症出现。结论:HIFU治疗子宫腺肌症疗效和安全性均较好,值得临床推广。
Objective: To observe the efficacy and safety of high intensity focused ultrasound in the treatment of adenomyosis. Methods: Sixty-eight patients with adenomyosis were treated with HIFU for 6 months. The clinical symptoms, laboratory tests and ultrasound images before and after treatment were compared. Results: The volumes of adenomyosis before and after HIFU treatment were (15.13 ± 5.9) cm ~ 3 and (10.62 ± 3.12) cm ~ 3, respectively, and the scores of dysmenorrhea were (2.35 ± 1.14) and (0.92 ± 0.77) The hemoglobin concentrations were (89.63 ± 7.25) g / L and (101.47 ± 6.87) g / L, respectively (P <0.01), and the differences were statistically significant. HIFU after treatment of abnormal menstruation, dysmenorrhea, abdominal bulge, bladder compression and other clinical symptoms were significantly relieved, no serious clinical adverse reactions and complications. Conclusion: HIFU treatment of adenomyosis efficacy and safety are good, worthy of clinical promotion.