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恶性肿瘤的形成与多种因素有关,是一个多步骤的过程,其中人类端粒酶逆转录酶在肿瘤形成中发挥重要的作用,主要通过激活端粒酶而维持端粒长度使细胞永生化或恶变,它可作为一种新的肿瘤标记物和肿瘤治疗的新靶点,也可作为检测和诊断口腔癌的有意义的指标。
The formation of malignant tumors is associated with a variety of factors and is a multi-step process in which human telomerase reverse transcriptase plays an important role in tumorigenesis by maintaining the telomere length by activating telomerase to immortalize cells or It can be used as a new tumor marker and a new target for tumor therapy, and it can be used as a meaningful indicator to detect and diagnose oral cancer.