生产车间的主要目的:(1)回顾和评估手头有关局部治疗药的资料;(2)评估药理活性、药物释放和临床效果之间的关系;(3)寻求局部治疗物向靶部位释放的最佳途径;(4)确定重要的优化原则;(5)提出有关局部或系统毒性问题;(6)讨论局部治疗评估中的利弊关系。目前,对于药物释放及运用模型(包括动物和数学模型)去预测和优化局部治疗药的 The main purpose of the workshop is to: (1) review and evaluate information on topical treatments on hand; (2) assess the relationship between pharmacological activity, drug release and clinical outcomes; (3) seek the release of topical treatments to target sites (4) identifying important optimization principles; (5) raising questions about local or systemic toxicity; and (6) discussing the pros and cons of the local treatment assessment. Currently, models of drug release and utilization, including animal and mathematical models, are used to predict and optimize the topical treatment of