肝脏Gd-DTPA快速动态增强MRI的临床应用──较小HCC与FNH的动态增强表现

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目的:运用梯度回波(GRE)的快速场回波(FFE)技术,对20例肝肿块进行Gd-DTPA动态增强,旨在探明不同肿块的增强规律,提高肝肿块的诊断和鉴别诊断能力。材料与方法:选取经过其他影像学检查未确诊的20例肝肿块,作常规自旋回波(SE)平扫后作Gd-DTPAFFE序列快速动态增强扫描,分别测量病灶信号强度(SIlesion),灶周正常肝脏信号强度(SIlivsr),背景噪声信号强度和标准差(SInoisec±s),计算不同病变不同时相的肝-病灶对比噪声比(C/N),描出不同肿块(本文只评价其中手术病理证实的13例肿块,包括肝细胞癌10例,局灶性结节增生3例的时间-病灶C/N曲线。结果:HCC与FNH两者曲线较接近(包括强化峰值和升降坡度),但在增强早期,HCC的C/N值高于FNH,3分钟以后二者强化值均下降,且FNH的C/N值大于0,HCC的C/N值小于0,此差异可持续15~20分钟。结论:不同的肝肿块,动态增强后的时间-C/N曲线不同,对HCC及FNH而言,增强早期(1分钟以内)及3分钟以后曲线差异较大,最有助于鉴别诊断。动态增强MR成像可作为肝脏常规SE序列成像的一种有效的补充方法。 Objective: To evaluate the enhancement of Gd-DTPA in 20 cases of hepatic masses using Gradient Echo (GRE) Fast Field Echo (FFE) technique, aiming at exploring the enhancement law of different masses and improving the diagnostic and differential diagnosis of hepatic masses. . Materials and Methods: Twenty hepatic masses not diagnosed by other imaging examinations were selected and subjected to conventional spin echo (SE) plain scans for rapid dynamic contrast-enhanced Gd-DTPAFFE scan. The signal intensity (SIlesion) of lesions was measured. Normal liver signal intensity (SIlivsr), background noise signal intensity and standard deviation (SInoisec±s), calculated liver-focal contrast to noise ratio (C/N) at different phases of different lesions, and mapped out different masses (this article only evaluated surgical pathology The 13 confirmed tumors included 10 cases of hepatocellular carcinoma and 3 cases of focal nodular hyperplasia with time-lesion C/N curve.Results: The curves of HCC and FNH were similar (including enhancement peak and elevation slope), but In the early stage of enhancement, the C/N value of HCC was higher than that of FNH. After 3 minutes, the two enhanced values ​​both decreased, and the C/N value of FNH was greater than 0, and the C/N value of HCC was less than 0. This difference is sustainable 15 to 20 Min. Conclusion: Different liver masses, dynamic enhancement The time-to-C/N curves are different, and for HCC and FNH, the differences between the early (within 1 minute) and 3 minutes later curves are larger, which is most helpful for differential diagnosis.The dynamic contrast-enhanced MR imaging can be used as a routine liver SE sequence imaging. An effective supplement method.
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作者报告了2例胰血管活性肠肽瘤,均具有典型胰血管活性肠肽瘤综合征且合并远处转移。2例均行手术及术后化疗,其中1例术前用生长抑素控制症状,手术切除肿瘤后症状改善明显。观察表明生长抑素对控制症状有明显效果,而早期诊断是决定预后的关键。作者结合文献对胰血管活性肠肽瘤的一般临床特点和诊治问题进行了探讨。