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1例44岁男性患者,椎管内神经鞘瘤术后给予头孢替安,复方甘露醇,并给予奥拉西坦4.0 g溶于5%葡萄糖注射液250 ml中静脉滴注。奥拉西坦开始滴注后约15 min患者出现全身抽搐,大汗淋漓,面部及四肢末梢发绀。立即停药,给予面罩吸氧。心电监护示血压90/60 mm Hg(1 mmHg=0.133 kPa),脉搏120次/min。给予肾上腺素1 mg静脉推注,0.9%氯化钠注射液500 ml快速滴注。10 min后血压80/50 mm Hg,血氧饱和度0.90。再次静脉推注肾上腺素1 mg,地塞米松5 mg。20 min后患者抽搐等症状缓解,血压升至100/75 mm Hg。
A 44-year-old man with neurilemmoma in the spinal canal was given cefotiam and compound mannitol after surgery. Oraliracetam 4.0 g dissolved in 250 ml of 5% glucose injection was given intravenously. About 15 minutes after oxiracetam began drip, patients developed generalized convulsions, sweating, and cyanosis of the face and extremities. Immediate withdrawal, to mask oxygen. ECG monitoring showed blood pressure 90/60 mm Hg (1 mmHg = 0.133 kPa), pulse 120 beats / min. Give epinephrine 1 mg intravenous bolus, 0.9% sodium chloride injection 500 ml rapid infusion. Blood pressure was 80/50 mm Hg after 10 min and oxygen saturation was 0.90. Again intravenous injection of epinephrine 1 mg, dexamethasone 5 mg. After 20 min, the symptoms such as convulsion were relieved and the blood pressure rose to 100/75 mm Hg.