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目的:检测新生儿溶血病(HDN)母体IgG抗A(B)抗体效价水平,探讨孕妇产前IgG抗体效价筛查在新生儿溶血病中预防的意义。方法:对我院72份“O”型孕妇样本进行母体IgG抗体效价检测。结果:孕妇抗体效价(IgG抗A(B)抗体)愈高,新生儿发生溶血病的几率愈高。结论:孕妇产前IgG抗体效价检测对新生儿溶血病的监测有指导作用,可作为判断胎儿出生后是否会发生新生儿溶血病的重要筛查项目。
Objective: To detect the antibody titer of neonatal hemolytic disease (HDN) maternal IgG anti-A (B) antibody and to explore the significance of prenatal IgG antibody titer screening in neonatal hemolytic disease. Methods: 72 samples of “O” pregnant women in our hospital were tested for maternal IgG antibody titer. Results: The higher the antibody titer of pregnant women (IgG anti-A (B) antibody), the higher the risk of hemolytic disease in the newborn. Conclusion: The detection of prenatal IgG antibody titer in pregnant women plays a guiding role in the monitoring of hemolytic disease in newborn. It can be used as an important screening item to determine whether newborn hemolytic disease occurs after birth.