托吡酯(topiramate,Topamax)片和胶囊的说明书中,警告和注意事项部分加强了服用后可引起患者视觉综合征(ocular syndrome)的信息。一项对825,000多名患者的监测显示,托吡酯作为治疗癫痫发作的辅助药物,可导致继发性闭角型青光眼,其特征是眼痛、急性近视及眼压升高。至2001年8月17日,己报道了23例服用托吡酯引起视觉综合征,其中1例是儿童。治疗视觉综合征的首要措施 In the instructions for topiramate (Topamax) tablets and capsules, the warnings and cautions in part reinforce the information that can cause ocular syndrome in patients after taking it. A survey of more than 825,000 patients showed that topiramate, as a secondary drug for the treatment of seizures, can lead to secondary angle-closure glaucoma, which is characterized by eye pain, acute myopia and elevated intraocular pressure. As of August 17, 2001, 23 cases of topical retinal superoxide dismutase (PVS) have been reported, of which 1 was a child. The first measure for the treatment of visual syndrome