论文部分内容阅读
在口服氯化铝导致学习记忆障碍模型的基础上，用跳台、避暗等实验方法观察了纳络酮对铝中毒小鼠学习记忆障碍的改善作用，并测定了肝丙二醇、脑B型单胺氧化酶的变化。实验结果显示，氯化铝可导致小鼠学习记忆障碍，以及增高丙二醛和B型单胶氧化酶的作用，而纳络酮对改善铝中毒小鼠学习记忆障碍有作用，同时有清除过氧化脂质和抑制B型单胶氧化酶活性的作用。
On the basis of the oral aluminum chloride induced learning and memory impairment model, the effect of naloxone on the learning and memory impairment in mice with aluminum poisoning was observed by jumping off and avoiding darkness, and the effects of hepatic propanediol, brain monoamine B monoamine oxidase Variety. Experimental results show that aluminum chloride can cause learning and memory disorders in mice, as well as increase the role of malondialdehyde and B-type mono-oxidase, while naloxone has an effect on improving learning and memory impairment in mice with aluminum toxicity, while clearance Lipid oxidation and inhibition of B-type mono-oxidase activity.