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巨细胞成纤维细胞瘤(GCF)是一种少见的 间叶肿瘤,报道1例CD34阳性的GCF,并提出“血管扩张样腔”形成的可能机制。 患者男,17岁。在过去数年中,腹部缓慢出现一个3.5cm大小的无痛结节。手术切除后28个月内无复发或转移。 大体标本,肿瘤为灰白色团块,位于真皮和皮下脂肪组织,不对称,边界不清,未见出血和坏死。镜下,肿瘤中央及周边的结构模式不同,中央由梭形细胞组成,嵌于纤维粘液样基质中,
Giant cell fibroblastoma (GCF) is a rare interlobar tumor. One case of CD34-positive GCF was reported and a possible mechanism for the formation of “vasodilator-like lumen” was proposed. Male patient, 17 years old. In the past few years, a 3.5cm painless nodule slowly appeared in the abdomen. There was no recurrence or metastasis within 28 months after surgical resection. In gross specimens, the tumors were gray-white masses, located in the dermis and subcutaneous adipose tissue. They were asymmetrical, with unclear boundaries and no hemorrhage and necrosis. Under the microscope, the central and peripheral tumors have different structural patterns. The center is composed of spindle cells embedded in a fibrinoid matrix.