论文部分内容阅读
目的:针对在产前诊断的过程当中使用超声检测同羊水染色体检查方式的临床价值进行分析和讨论。方法:选取2014年1月至2016年1月期间在我院接受产检的600名唐筛高危孕妇,行以超声同羊水染色体检查,超声结果当中发现胎儿异常35例,同时行以羊水染色体检测,经过引产(或者分娩)后的病理学检查,确诊共24名,将其设为实验组;同时择取超声检查结果正常,并同意行羊水染色体检测的105名孕妇,将其设为参照组。结果:常见的超声检查畸形结果包括:脑积水、脊柱裂、心脏畸形、脐膨出、唇裂、脊柱裂同脑积水、脑膜膨出等。实验组当中胎儿的染色体异常概率为68.57%(24/35),参照组当中则为0.95%(1/105),对比P<0.001。结论:在临床当中,可以将超声检测作为辅助诊断胎儿染色体是否存在异常情况的措施,如果结合羊水染色体检测,能够很好的提升诊断染色体异常的准确率,值得推广和应用。
OBJECTIVE: To analyze and discuss the clinical value of ultrasonographic detection of amniotic fluid chromosome in prenatal diagnosis. Methods: From January 2014 to January 2016 in our hospital during the inspection of 600 Tang screening high-risk pregnant women, line ultrasound with amniotic fluid chromosome examination, ultrasound findings were found in 35 cases of fetal abnormalities, at the same time with amniotic fluid chromosome test, A total of 24 confirmed cases were diagnosed after induced labor (or childbirth), and were selected as the experimental group. 105 pregnant women with normal ultrasound examination and consenting to amniocentesis were also selected as the reference group. Results: The common ultrasonic examination deformity results include: hydrocephalus, spina bifida, cardiac deformity, umbilical swelling, cleft lip, spina bifida with hydrocephalus, meningeal bulging and so on. Fetal chromosomal abnormalities in the experimental group, the probability of 68.57% (24/35), while the reference group was 0.95% (1/105), P <0.001. Conclusion: Ultrasound can be used as an auxiliary measure to diagnose fetal chromosomal abnormalities in clinical practice. If combined with amniotic fluid chromosomal detection, the accuracy of chromosomal abnormalities diagnosis can be well promoted, which is worthy of popularization and application.