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研究了用毛细管区带电泳法快速测定复方布洛芬片中布洛芬和伪麻黄碱含量的方法。在０．０２５ｍｏｌ／Ｌ的磷酸盐缓冲液（ｐＨ８．１）中，上述两组分可在３ｍｉｎ内得以完全分离，用紫外检测器在２１０ｎｍ处检测，并以外标法定量。１１次测定含有９．５ｍｇ／Ｌ盐酸伪麻黄碱和６６．７ｍｇ／Ｌ布洛芬的试样溶液，相对标准偏差为２．９％（伪麻黄碱）和１．９％（布洛芬），回收率为１０３．１％（伪麻黄碱）和９７．６％（布洛芬）。应用毛细管区带电泳法测定复方布洛芬片剂的含量，所得结果与ＨＰＬＣ法一致。
A method for the rapid determination of ibuprofen and pseudoephedrine in compound ibuprofen tablets by capillary zone electrophoresis was studied. In 0.025mol / L phosphate buffer (pH8.1), the above two components can be completely separated in 3min, with UV detector detection at 210nm, and the external standard method. Eleven measurements of test solutions containing 9.5 mg / L pseudoephedrine hydrochloride and 66.7 mg / L ibuprofen showed relative standard deviations of 2.9% (pseudoephedrine) and 1.9% (ibuprofen) with a recovery of 103.1% (pseudoephedrine) and 97.6% (ibuprofen). The content of compound ibuprofen tablets was determined by capillary zone electrophoresis. The obtained results were consistent with those of HPLC method.