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目的 通过对北京市西城区2012-2016年12岁以下儿童手足口病流行特征的调查,为辖区手足口病的防控工作提供有利依据.方法 从中国疾病预防控制信息系统中导出2012-2016年北京市西城区手足口病的发病资料,采用Excel 2007软件进行数据整理,以SPSS 21.0软件进行数据分析,运用描述流行病学方法分析流行规律.结果北京市西城区12岁以下儿童2012-2016年各年手足口病均有病例报告,共计5 534例,存在夏秋季高发特征,区域交汇街道的发病明显多于中心街道.5岁以下儿童报告手足口病发病最多,为4 698例,占84.89％,其中尤以3～4岁组儿童发病最多(2 052例);男女儿童性别比为1.45∶1;以托幼儿童发病占比最高(47.79％).结论 北京市西城区2012-2016年12岁以下儿童手足口病的发病有明显的地区、年龄、季节及生长环境差别,5岁以下托幼儿童的手足口病防控工作应为当前西城区手足口病防控工作的重点.“,”Objective To analyze epidemiological characteristics of the hand foot and mouth disease ( HFMD) of children under 12 years old in Xicheng district of Beijing during 2012 and 2016, provide evidence for the prevention and control of HFMD. Methods The data of HFMD from the disease prevention and control system of Beijing during 2012 and 2016 were gathered and disposed by Excel 2007 and were analyzed by SPSS 21. 0. Results From 2012 to 2016, every year HFMD cases under 12 years old had occurred in Xicheng district, total of 5534 cases and had obvious characteristics in summer and autumn. The children under 5 years old were mostly affected ( 4698). While the highest incidence were children between 3 to 4 years old ( 2052). There were more incidence in boys than in girls, the sex ratio was 1. 45∶ 1. The young children were in the majority ( 47. 79％). Conclusion HFMD incidence under 12 years old in Xicheng of Beijing from 2012 to 2016 had significant different in area, age, season and growing environment. Young children under 5 years old are the main point of HFMD prevention and control.