胃食管显像评价慢性呼吸道疾病患儿的胃食管反流(摘要)

来源 :上海医科大学学报 | 被引量 : 0次 | 上传用户:A13808289587
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用放射性核素胃食管显像评价慢性呼吸道疾病患儿胃食管反流 (GER) ,并观察抗反流药西沙比利对该症的疗效。方法 对 45例慢性呼吸道疾病患儿进行99mTc DTPA胃食管显像 ,并与 8例正常儿童进行比较。对部分GER患儿经西沙比利治疗 3个月后重复显像。结果 发现 2 5例 (5 5 % )患儿存在GER ,8例正常儿童均不存在GER。对 10例GER患儿用西沙比利治疗 3个月后 ,复查胃食管显像 ,发现 7例患儿GER消失 ,同时呼吸道症状明显好转。结论 慢性呼吸道疾病患儿中有相当一部分存在GER ;用西沙比利治疗不仅可缓解GER ,同时可改善呼吸系症状。 Gastroesophageal reflux (GER) in children with chronic respiratory diseases was evaluated by radionuclide gastro-esophageal imaging and the effect of anti-reflux drug cisapride on the disease was observed. Methods Forty-five children with chronic respiratory diseases underwent 99mTc DTPA gastro-esophageal imaging and compared with 8 normal children. Some patients with GER were treated with cisapride 3 months after repeated imaging. Results GER was found in 25 (55%) children and none in 8 normal children. After 10 months of treatment with cisapride in 10 children with GER, gastroesophageal imaging was reviewed. The GER disappeared in 7 children and the respiratory symptoms improved significantly. Conclusion A considerable proportion of children with chronic respiratory diseases have GER. Treatment with cisapride can not only relieve GER, but also improve respiratory symptoms.
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