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为了研究间接包装材料中光引发剂(PIs)的迁移规律,建立了采用改性聚苯醚(MPPO)作为模拟物的迁移实验方法,并通过气相色谱-串联质谱(GC-MS/MS)联用技术测定了18种PIs的特定迁移量。间接包装材料中迁移出的PIs被MPPO吸附后,用乙腈萃取,萃取液用正己烷-乙酸乙酯(3∶7,体积比)进行溶剂置换后,经有机滤膜过滤和DB-5MS弹性毛细管色谱柱分离后,采用串联质谱法分析,内标法定量。结果表明:①18种PIs在26 min内有效分离,且在0.01~5.00 mg/L范围内线性关系良好(R2>0.997)。加标回收率在86.4%~123.8%之间,相对标准偏差(RSD)<8.3%,检出限(LOD)为0.001~0.021 mg/kg。②迁移量在0.02~30.00μg/g时,该测试方法相对重复性标准偏差在6.3%~21.4%之间,相对再现性标准偏差在13.5%~22.3%之间。③实际样品PIs的迁移率与其分子量和沸点显著负相关。4真空镀铝内衬纸可以有效地阻隔PIs的迁移。
In order to study the migration of photoinitiators (PIs) in indirect packaging materials, a migration experiment using modified polyphenylene ether (MPPO) as a mimic was established and analyzed by gas chromatography-tandem mass spectrometry (GC-MS / MS) The specific migration of 18 PIs was determined by the technique. The PIs migrated from the indirect packaging material were adsorbed by MPPO and extracted with acetonitrile. After the solvent was replaced by n-hexane-ethyl acetate (3: 7, volume ratio), the PIs were filtered through an organic membrane filter and subjected to capillary electrophoresis Column separation, the use of tandem mass spectrometry analysis, internal standard method. The results showed that: ①18 kinds of PIs were effectively separated within 26 min, and the linearity was good in the range of 0.01 ~ 5.00 mg / L (R2> 0.997). The spiked recoveries ranged from 86.4% to 123.8% with relative standard deviations (RSDs) <8.3% and limit of detection (LOD) from 0.001 to 0.021 mg / kg. ② The relative standard deviation (RSD) of the test method was between 6.3% and 21.4% and the relative standard deviation of reproducibility was between 13.5% and 22.3% at the range of 0.02 ~ 30.00 μg / g. ③ The actual sample PIs mobility and its molecular weight and boiling point significantly negatively correlated. 4 vacuum aluminum lining paper can effectively block the PIs migration.