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临床上治疗慢性肺心病伴发心衰颇为棘手,疗效不尽人意。常用的强心药如:洋地黄类、儿茶酚胺类药。前者在人体缺氧状态时易中毒,用量受到限制;后者能兴奋β-受体,明显提高心率,易致心律失常,加重心肌缺氧和心衰,胰高血糖素正性肌力作用弱,得不到广泛的应用。而氨力农为非洋地黄、非凡茶酚胺及非胰高血糖素类新型正性肌力药物。作者试用氨力农治疗慢性肺心病伴心衰35例,疗效明显高于对照组,现报告如下。
Clinical treatment of chronic pulmonary heart disease with heart failure is quite difficult, the effect is not satisfactory. Common cardiac drugs such as: digitalis, catecholamines. The former is poisoned in the hypoxic state of the human body, the dosage is limited; the latter can be excited β-receptor, significantly improve heart rate, prone to arrhythmia, increased myocardial hypoxia and heart failure, glucagon positive inotropic effect is weak , Can not get a wide range of applications. The amrinone is non-digitalis, phenylephrine and non-glucagon new inotropic drugs. The author tried ammonia force to treat chronic pulmonary heart disease with heart failure in 35 cases, the effect was significantly higher than the control group, are as follows.