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本文动态观察急性心肌梗塞(AMI)患者30例发病第1、2、3、7、14、28天和不稳定性心绞痛(UA)10例心绞痛持续发作时体外血栓的变化,并与正常人作对照。结果,AMI、UA组血栓值(长度、千重)均较正常人组明显升高(P<0.01)。AMI第3天血栓值最高,7天后呈下降趋势。体外血栓值的升高与AMI的梗塞面积、并发症的严重程度以及CPK活性呈正相关。血栓值持续升高者预后不良。研究表明:UA、AMI患者的血液呈高凝状态,易于形成血栓。早期对UA、AMI患者抗凝、溶治)疗可改善预后。
This article dynamically observed 30 cases of patients with acute myocardial infarction (AMI) onset 1, 2, 3, 7, 14, 28 days and unstable angina (UA) 10 cases of continuous episodes of angina pectoris changes in vitro thrombosis, and with normal Control. Results, thrombus value (length, thousandth) in AMI and UA groups were significantly higher than those in normal people (P <0.01). The thrombosis value of AMI was the highest on the third day, and decreased after 7 days. The increase of thrombus in vitro was positively correlated with infarct size, the severity of complications and CPK activity in AMI. Prolonged thrombus values have a poor prognosis. Studies have shown that: UA, AMI patients with hypercoagulable blood state, easy to form thrombus. Early UA, AMI patients with anticoagulation, dissolved treatment) can improve the prognosis.