【据《Virology》2014年6月报道】题:基因1~6型无血清HCV颗粒培养体系的建立和特点(作者Mathiesen CK等)最近产生HCV颗粒(HCVcc)的细胞培养系统已经建立。构建无血清培养环境可能是制造无活性全病毒疫苗好的发展方向。来自Hvidovre医院的Mathiesen CK等描述了通过Huh7.5细胞培养于腺病毒表达介质获得基因型1~6型的无血清HCVcc(sf-HCVcc)。与HCVcc相比,sf-HCVcc显示出0.6~2.1l g倍的感染性滴度 Virology, June 2014 Report Title: Establishment and Characterization of Gene-Type 1 to 6 Serum-free HCV Particle Cultures by Mathiesen CK et al. A recent cell culture system for the production of HCV particles (HCVcc) has been established. Building a serum-free culture environment may be a good direction for the development of an inactive whole virus vaccine. Mathiesen CK et al from Hvidovre Hospital describe the generation of serum-free HCVcc (sf-HCVcc) of genotypes 1 to 6 by culturing the adenovirus expression vector in Huh7.5 cells. Compared to HCVcc, sf-HCVcc showed an infectivity titer of 0.6-2.1 lg