目的　建立同种异体肢体移植的动物模式。　方法　Wistar大鼠的肢体移植给SD大鼠 ,术后抗炎 ,显微外科常规护理 ,观察移植后宿主及移植物的变化。　结果　大鼠的异体肢体移植 8例 ,成功 6例 ;移植物的排斥反应再现稳定 ,生存时间为 (14± 2 )d。　结论　Wistar→SD大鼠的同种异体肢体移植模型的建立 ,为基础研究提供了动物模型 Objective To establish an animal model of allograft limb transplantation. Methods The limbs of Wistar rats were transplanted to SD rats. After anti-inflammatory and microsurgical routine nursing, the changes of host and graft after transplantation were observed. Results Allograft limb transplantation in 8 cases, successful in 6 cases; rejection of graft reproduction stable, survival time was (14 ± 2) d. Conclusion The establishment of Wistar → SD rat allograft model provides animal models for basic research