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目的 :观察糖皮质激素性青光眼视盘损害与用药时间的关系。方法 :对随访观察资料完整的糖皮质激素性青光眼 5 0例 98眼进行分析。结果 :青少年和男性患者较多 ,平均年龄 2 0 .3± 2 2 .2岁 ,男女之比为 3.2∶ 1。连续用药 6个月以上即可出现视盘病理性改变。视盘及视野损害的程度随用药时间的增加而增加。用药时间 1年以上和少于 1年者 ,C/ D≥ 0 .6者分虽为 80 .7%和 2 6 .7% (P<0 .0 0 5 ) ,视野损害者分别为 84.3%和 2 6 .7% (P<0 .0 0 5 )。双眼用药者双眼视盘及视野改变不一致者占 5 6 % 3%。结论 :该病多发生于男性青少年。视盘损害的程度与用药时间明显相关。双眼用药者 ,半数以上双眼视盘及视野改变不一致
Objective: To observe the relationship between optic disc damage and medication time in glucocorticoid-induced glaucoma. Methods: Fifty-98 eyes of 50 cases with complete glucocorticoid glaucoma were followed up. Results: There were more adolescents and males with an average age of 20.3 ± 2.2 years and a ratio of men to women of 3.2: 1. Continuous medication for more than 6 months can appear pathological changes in optic disc. The extent of optic disc and visual field damage increased with the increase of medication time. Medication time of more than 1 year and less than 1 year, C / D≥0.6 Although the scores were 80.7% and 26.7% (P0.005), visual field damage were 84.3% And 26.7% (P <0.05). Binocular binocular vision and visual field change inconsistent patients accounted for 56% 3%. Conclusion: The disease occurs mostly in male adolescents. The degree of optic disc damage was significantly related to the duration of the medication. Binocular medication, more than half of the binocular optic disc and visual field inconsistent changes