四氯乙烯是目前驱除钩虫较重要的药物之一,解放后我国曾大规模应用它来治疗钩虫病,获得很大的效果,与其他的驱虫药物相比,它的作用较土荆芥油为好。其作用与四氯化碳相似,但服后比四氯化碳吸收稍慢,故毒性小得多。四氯乙烯不溶于水,而易溶于脂肪和乙醇中;在一般情况下,口服四氯乙烯不会被胃肠道所吸收,因此比较安全。迄今在国内治疗数千万的钩虫病病例中,尚无因服药中毒死亡的报道。但应注意的是,服药方法和剂量的恰当与否,却与其毒性反应有很大的关系。例如,在服药期间及其前后,病人食用较多的油类、含脂肪丰富的食物或酒类,则能促进四氯乙烯的被吸收,以致引起一些毒性反应。按我国人民一般体重计算,每 Perchlorethylene is currently one of the more important drugs to exterminate hookworm. After its liberation, it has been applied to treat hookworm disease on a large scale and achieved great results. Compared with other deworming drugs, its effect is stronger than that of soil Nepeta Oil is good. Its role and carbon tetrachloride similar, but slightly slower than after taking carbon tetrachloride, so the toxicity is much smaller. Tetrachlorethylene is insoluble in water and soluble in fat and ethanol; in general, oral PCE is not absorbed by the gastrointestinal tract and is therefore safer. So far in the domestic treatment of tens of millions of cases of hookworm disease, there is no report of death due to medication poisoning. It should be noted, however, that proper dosing methods and doses are strongly related to their toxicity. For example, patients taking more oil, fat-rich foods or alcohol during and before taking medication can promote the absorption of PCE and cause some toxic reactions. According to the general weight of our people, each