老年肝门部胆管癌的临床特点与治疗

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背景与目的:老年肝门部胆管癌的发病率有上升趋势,由于老年人的病理、生理及其病变的解剖特点,手术切除率极低,而以各种引流术辅以术后放化疗为主。本研究探讨老年肝门部胆管癌的临床特点及有效治疗方法。方法:回顾性分析本院1995年1月到2005年12月共收治的28例老年人(≥60岁)肝门部胆管癌的临床资料。结果:共3例行胆管癌切除,术后两例存活超过3年,手术探查3例,存活时间1~2个月,其余22例均行胆道内或外引流,辅以放疗,存活时间在5个月到48个月,平均13.2个月。结论:外科手术仍是治疗肝门部胆管癌的有效治疗手段。对无法切除者,行各种引流手术,辅以放化疗,可以改善患者的生存质量、延长生存时间。 BACKGROUND & OBJECTIVE: The incidence of hilar cholangiocarcinoma in the elderly is on the rise. Due to the anatomical characteristics of the pathology, physiology and pathology of the elderly, the surgical resection rate is extremely low. However, all kinds of drainage combined with postoperative radiotherapy and chemotherapy the Lord. This study was to explore the clinical features and effective treatment of elderly patients with hilar cholangiocarcinoma. Methods: The clinical data of 28 elderly patients (≥60 years) with hilar cholangiocarcinoma who were treated in our hospital from January 1995 to December 2005 were retrospectively analyzed. Results: A total of 3 patients underwent cholangiocarcinoma resection. Two patients survived for more than 3 years after operation. Surgical exploration was performed in 3 patients and the survival time was 1 to 2 months. The remaining 22 patients underwent biliary or external drainage with radiotherapy. The survival time was 5 months to 48 months, an average of 13.2 months. Conclusion: Surgery is still an effective treatment for hilar cholangiocarcinoma. Can not be removed, a variety of drainage surgery, combined with radiotherapy and chemotherapy, can improve the quality of life of patients and prolong survival time.
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