轮状病毒是婴幼儿秋冬季腹泻的最常见的病原。我们用ＥＬＩＳＡ试剂盒对５４例大便常规检查无ＷＢＣ或偶见的疑似轮状病毒腹泻患儿进行了轮状病毒病原学检测，从中检出轮状病毒阳性患儿４８例，被确诊为轮状病毒肠炎。结果显示粪便中轮状病毒滴度越高，其临床症状也相应越重。此４８例患儿均采用病毒唑、双歧杆菌活菌制剂、补液纠正脱水等综合治疗，其中３０例辅以消化道粘膜保护剂思密达治疗，治疗组显效率为６０％，而对照组为１１．１％，经ｔ检验两组间显效率及总有效率均有非常显著性差异。表明思密达用于轮状病毒肠炎的治疗是一种较为有效的方法。 Rotavirus is the most common cause of diarrhea in infants and young children in autumn and winter. We used ELISA kit for 54 cases of stool routine examination without WBC or occasional suspected rotavirus diarrhea in children with rotavirus etiology detected from rotavirus-positive children in 48 cases were diagnosed as round Virus enteritis. The results showed that the higher the rotavirus titer in feces, the more severe the clinical symptoms. The 48 patients were treated with ribavirin, live bifidobacterium preparations, fluid replacement dehydration and other comprehensive treatment, of which 30 cases supplemented with gastrointestinal mucosal protective agent Smectite treatment group was markedly effective rate was 60%, while the control group 11.1%. There was a significant difference between the two groups by t-test in terms of significant and total effective rate. Smectite shows that the treatment of rotavirus enteritis is a more effective method.