Design,synthesis and insecticidal activities of novel anthranilic diamides containing fluorinated gr

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:zheng829
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In order to search for novel potent and environmentally benign insecticides,a series of anthranilic diamides containing various fluorinated groups were designed and synthesized.Their structures were confirmed by ~1H NMR,~(13)C NMR,~(19)F NMR,elemental analysis,HRMS or mass spectra.Their insecticidal activities against oriental armyworm(Mythimna separata) and diamondback moth(Plutella xyiostella)were evaluated.The preliminary structure-activity relationship(SAR) was discussed in detail.The biological assay indicated that most of the compounds exhibited moderate to excellent insecticidal activities.Especially,Ia showed high larvicidal activity against oriental armyworm.Meanwhile,Iu had better larvicidal effects against diamondback moth than commercial chlorantraniliprole. In order to search for novel potent and environmentally benign insecticides, a series of anthranilic diamides containing various fluorinated groups were designed and synthesized. Their structures were confirmed by ~ 1H NMR, ~ (13) C NMR, ~ (19) F NMR, elemental analysis, HRMS or mass spectra.Their insecticidal activities against oriental armyworm (Mythimna separata) and diamondback moth (Plutella xyiostella) were evaluated.The preliminary structure-activity relationship (SAR) was discussed in detail. The biological assay indicates that most of the compounds exhibited moderate to excellent insecticidal activities. Especially, Ia showed high larvicidal activity against oriental army worm. Meanwhile, Iu had better larvicidal effects against diamondback moth than commercial chlorantraniliprole.
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