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目的:探讨188Re放射性食管支架的辐射场特性,为该技术的临床应用提供科学依据。方法:利用核探测技术对仿生食管体模各代表位点测量其β和γ射线、韧致辐射剂量,并以数学公式模拟、绘制计算机软件。结果:188Re放射性支架的辐射场有其特性,β射线最大射程为11.mm,90%剂量建成区在1.5mm之内,95%剂量在2.5mm范围之内,而在6.5mm射程外的γ射线、韧致辐射能量仅占总剂量的4.21%。支架0°、90°、180°、270°平行点间轴向距离的吸收剂量均匀平衡一致,P>0.05。结论:188Re支架辐射以β射线为主体,γ射线、韧致辐射份额为4.21%。最大剂量建成区恰好落在食管粘膜层0.5-1.5mm范围内,适合为食管癌姑息性腔内放射治疗核素。
Objective: To investigate the radiation field characteristics of 188Re radioactive esophageal stent and provide a scientific basis for its clinical application. Methods: The β, γ-ray and bremsstrahlung dose of each phantom of bionic esophageal phantom was measured by nuclear detection technique, and the mathematical software was used to simulate and draw the computer software. Results: The radiation field of 188Re radioactive stent has its own characteristics. The maximum range of beta ray is 11.mm, the built-up area of 90% dose is within 1.5mm, the 95% dose is within 2.5mm, and γ Ray, bremsstrahlung radiation energy accounted for only 4.21% of the total dose. Stent 0 °, 90 °, 180 °, 270 ° parallel to the axial distance between the absorbed dose uniform balance, P> 0.05. Conclusion: The radiation of 188Re stent is mainly β ray, and the proportion of γ ray and bremsstrahlung radiation is 4.21%. The maximum dose of built-up area just falls in the esophageal mucosa 0.5-1.5mm range, suitable for esophageal cancer palliative intraluminal radiation therapy nuclide.