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许多报道示血浆置换(PP)治疗活动性系统性红斑狼疮有效,但对狼疮性肾炎(LN)行PP指征没有明确的标准。本文作者为了决定LN做PP的指征的标准,对35名进行PP治疗的病人做肾功能(F),尿蛋白(P),免疫活性(A)和肾脏组织学四方面的研究。根据肾功能程度把病人分四组:F_1(稳定的慢性肾功能衰竭或稳定的肾功能C_(cr)>50ml/分,n=14),F_2(复发型,C_(cr)30～50ml/分,n=9),F_3(快速进展型,C_(cr)<40ml/分,n=7)和F(急性肾功能衰竭,C_(cr)<10ml/分,n=6)。根据尿蛋白把
Many reports suggest that plasma exchange (PP) is effective in the treatment of active systemic lupus erythematosus, but there is no clear standard for PP indications for lupus nephritis (LN). In order to determine the criteria for LN to be a PP marker, the authors performed a study of renal function (F), urinary protein (P), immunocompetence (A), and renal histology in 35 PP-treated patients. According to the degree of renal function, the patients were divided into four groups: F_1 (stable chronic renal failure or stable renal function C_ (cr)> 50ml / min, n = 14) (N = 9, n = 9), F_3 (rapid progression, C_ (cr) <40 ml / min, n = 7) and F (acute renal failure, cr <10ml / min, n = 6). According to urinary protein put