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[目的]分析恶性纤维组织细胞瘤手术加放疗的疗效。[方法]1984年至1995年共26例恶性纤维组织细胞瘤进行了手术及术后放疗。手术采用局部广泛切除术。放疗采用高能X线、e线或60Coγ射线 ,常规分割 ,肿瘤量50Gy～70Gy。[结果]中位随访期5 3年。全组5年生存率、复发率和转移率分别为 :68 5 %、26 9 %和19 2 %。其中首次手术加术后放疗及多次手术加术后放疗的5年复发率分别为 :6 7%及54 5 % ,有显著性差异(P<0 01)。[结论]恶性纤维组织细胞瘤首次手术后并用放疗是较为可行的治疗方法 ,可以明显降低局部复发率。
[Objective] To analyze the effect of surgery and radiotherapy for malignant fibrous histiocytoma. [Methods] From 1984 to 1995, 26 cases of malignant fibrous histiocytoma underwent surgery and postoperative radiotherapy. Surgery was performed with extensive local resection. Radiotherapy using high-energy X-ray, e-ray or 60Co γ-ray, conventional segmentation, tumor volume 50Gy ~ 70Gy. [Results] The median follow-up period was 53 years. The 5-year survival rate, recurrence rate and metastasis rate in the whole group were: 68.5%, 26.9%, and 19.2%. The 5-year recurrence rates of the first surgery plus postoperative radiotherapy and multiple surgery plus postoperative radiotherapy were 67% and 54.5%, respectively, with significant differences (P<0.01). [Conclusion] Malignant fibrous histiocytoma combined with radiotherapy after the first operation is a feasible treatment and can significantly reduce the local recurrence rate.