【摘 要】
:
A series of novel polyphosphonates containing 5-flouro- N1-furanyl-N3- glyceroalkyl-uracil and formyl groups was synthesized by the condensation of 3-(w- (1¢-fur
【机 构】
:
Institute and National Key Laboratory of Elemento-Organic Chemistry
论文部分内容阅读
A series of novel polyphosphonates containing 5-flouro- N1-furanyl-N3- glyceroalkyl-uracil and formyl groups was synthesized by the condensation of 3-(w- (1¢-furanyl-5-flourouracil-3-yl) alkoxy)-1, 2-dihydroxy propane with phosphonyl dichloride. The products were characterized by IR, 1H NMR, 31P NMR, , and elemental analysis. The results of bioassay show that compound 8a possesses potential anticancer activity.
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