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目的调查糖尿病(DM)患者视网膜病变(DR)的发病率,并探讨其与各相关因素的关系。方法对140例糖尿病患者散瞳检查眼底。24例作眼底荧光造影检查。使用彩色多普勒对30例作眼部血动力学测定,并与18例正常人作对照。结果280只眼中91只眼患有不同程度的DR,发病率为32.5%,随着年龄的增长DR发病率增高,病程低于5年DR发病率为20.6%,大于15年为66.7%,血糖控制在正常范围以下者DR的发病率明显低于控制不良者,两者分别为 20.4%以下及 55. 6%。 DR组视力在 0. 3以下者占 32%,而 NDR组仅为 9. 5%,两者间有显著性差异。DR组的 PSV及EDV显著低于正常人及 NDR组,有显著性差异。结论糖尿病性视网膜病变发病率的高低与病程长短、血糖控制的好坏呈正相关的关系。彩色多普勒(CDI)可作为反映早期糖尿病眼部微循环状态提供了有效的检测手段。
Objective To investigate the incidence of retinopathy (DM) in diabetic patients and explore its relationship with various related factors. Methods 140 cases of diabetic patients dilated eye examination. 24 cases of fundus fluorescein angiography. Color Doppler echocardiography was performed on 30 eyes and compared with 18 healthy controls. Results 91 eyes of 280 eyes had different degrees of DR, the incidence was 32.5%. The incidence of DR increased with age. The incidence of DR was lower than 5 years and the incidence of DR was 20.6% and more than 15 years 66.7%. The incidence of DR was significantly lower than that of the control subjects with blood glucose control below the normal range, which were below 20.4% and 55 respectively. 6%. DR group visual acuity in 0. 3 below 32%, while NDR only 9. 5%, there is a significant difference between the two. The PSV and EDV in DR group were significantly lower than those in normal and NDR group, with significant difference. Conclusion The incidence of diabetic retinopathy and duration of disease, blood glucose control is positively correlated with the quality of the relationship. Color Doppler (CDI) can be used as a reflection of early diabetic eye microcirculation provides an effective means of detection.