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目的:研究米索前列醇联合丙泊酚在人流术扩宫困难时的应用效果。方法:2003年3月~2005年4月在我院门诊行人工流产术扩宫困难的56例患者,采用米索前列醇200μg碾碎后置于阴道后穹窿,3 h后在丙泊酚静脉麻醉下施行手术,观察宫颈扩张情况、出血量、子宫收缩、麻醉效果和药物的副反应及其他并发症。结果:丙泊酚镇痛效果满意,能有效防止人工流产综合征的发生,但无宫颈松弛作用;米索前列醇可以显著软化和扩张宫颈,使子宫收缩变硬,防止术中子宫穿孔,减少宫颈损伤等并发症的发生,且出血量明显减少。结论:米索前列醇和丙泊酚联合应用于人流术扩宫困难时,即达到了镇痛的效果,又达到扩张宫颈口的目的,而且在促进子宫收缩,减少术中出血,预防并发症的发生中起到了重要作用。
Objective: To study the effect of misoprostol combined with propofol on the difficulty of abortion during abortion. Methods: From March 2003 to April 2005, 56 patients with dilatation of abortion underwent abortion in our hospital were crushed with 200μg of misoprostol and placed in the posterior vaginal fornix. After 3 hours, Under anesthesia underwent surgery to observe cervical dilatation, bleeding, uterine contractions, anesthetic effects and side effects of drugs and other complications. Results: Propofol analgesic effect is satisfactory, can effectively prevent the occurrence of induced abortion syndrome, but no cervical relaxation; misoprostol can significantly soften and dilate the cervix, the contraction of the uterus hardens to prevent intraoperative uterine perforation and reduce Cervical injury and other complications, and significantly reduced bleeding. Conclusion: The combination of misoprostol and propofol in abortion difficult to achieve the effect of analgesia, but also to achieve the purpose of expanding the cervix, but also to promote uterine contraction, reduce intraoperative bleeding and prevent complications Occurrence has played an important role.