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为探讨血清中抗子宫内膜抗体(EMAb)与不孕的关系,检测200例不明原因不孕症妇女(不孕组)及41例健康孕妇(对照组)血清中EMAb。同时对不孕组中98例原发不孕妇女及62例人流(吸/刮宫)术后继发不孕妇女血清中EMAb的检测结果进行了比较。结果显示:对照组血清EMAb阳性率24%;不孕组血清EMAb阳性率2800%,明显高于对照组(P<001)。不孕组中原发不孕患者血清EMAb阳性率1735%;人流(吸/刮宫)术后继发不孕妇女血清EMAb阳性率高达3709%,显著高于原发不孕组。结论:不明原因不孕症妇女体内存在着一定程度上的免疫功能紊乱,EMAb的产生可能是导致不孕的原因之一,而人流术是促使EMAb产生的原因之一。
In order to explore the relationship between serum anti-endometrial antibody (EMAb) and infertility, EMAb was detected in sera of 200 women with unexplained infertility (infertility group) and 41 healthy pregnant women (control group). At the same time, 98 cases of infertile women with primary infertility and 62 cases of flow (suction / curettage) postoperative infertility women serum EMAb test results were compared. The results showed that the positive rate of serum EMAb in control group was 24%; the positive rate of serum EMAb in infertility group was 2800%, which was significantly higher than that of control group (P <001). The positive rate of serum EMAb in infertility patients was 17.35%. The positive rate of serum EMAb in post-infertile women (37.9%) was significantly higher than that of primary infertility patients after abortion (suction / curettage). Conclusion: There is a certain degree of immune dysfunction in women with unexplained infertility. EMAb may be one of the causes of infertility, and artificial abortion is one of the reasons for EMAb.