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目的 分析手术、化疗联合治疗腮腺癌的效果。方法 术前或术中通过病理诊断将 92例腮腺癌分为低度恶性和高度恶性两种。低度恶性行腺叶及肿瘤切除术 ;高度恶性宜扩大切除。对淋巴结阳性者和Ⅲ～Ⅳ期高度恶性者应行腮颈联合根治术。术后在身体、血象允许情况下给予化疗 ,分局部化疗和全身化疗二种。结果 92例腮腺癌 5年、10年生存率分别为 72 8%、5 8 7% ,其中低度恶性者 5年、10年生存率分别为 95 1%、82 9% ;高度恶性者 5年、10年生存率分别为 5 8 3 %、43 1%。总淋巴结转移率为 2 5 0 %。结论 将腮腺癌治疗区分为低度恶性和高度恶性是可行的。合并化疗做为辅助性治疗是必要的 ,它可明显降低术后复发率 ,提高 5年、10年生存率。
Objective To analyze the effect of surgery and chemotherapy in the treatment of parotid gland carcinoma. Methods 92 cases of parotid gland carcinoma were divided into two kinds of low grade and high degree of malignancy by pathological diagnosis before or during operation. Low grade malignant gland leaf and tumor resection; high degree of malignancy should expand the resection. Lymph node positive and Ⅲ ~ Ⅳ highly malignant should be combined parotid neck radical mastectomy. After surgery in the body, blood to allow the case given chemotherapy, sub-local chemotherapy and systemic chemotherapy in two. Results 92 cases of parotid gland carcinoma had a 5-year and 10-year survival rates of 72.8% and 58.7%, respectively. The 5-year and 10-year survival rates of 95 cases were 95.1% and 82.9% respectively for those with low-grade malignancy and 5-year The 10-year survival rates were respectively 58.3% and 43.1%. The total lymph node metastasis rate was 25.0%. Conclusions It is feasible to classify the treatment of parotid gland as low grade and high grade. Chemotherapy combined with adjuvant therapy is necessary, it can significantly reduce the recurrence rate and improve 5-year, 10-year survival rate.