The levels of common pesticides and heavy metals in Dendrobium officinale grown from 2012 to 2014 were measured, and three planting methods were used in 2014. The quality of plant husbandry improved during the study period. Thirteen types of pesticides were detected in D. officinale grown in 2014 and antimicrobials, including carbendazim, difenoconazole and azoxystrobin, were evident in 61.53% of plants. These three pesticides constituted 72.33% of all the antimicrobials detected. Planting methods affected the levels of pesticides and heavy metals. Trellising in plastic sheds was optimal, being associated with the lowest amounts of both pesticides and heavy metals. Both cadmium(Cd) and lead(Pb) levels were high in treed plants, whereas Cr, As and Cu levels were the highest in potted plants. The levels of common pesticides and heavy metals in Dendrobium officinale grown from 2012 to 2014 were measured, and three planting methods were used in 2014. Thirteen types of pesticides were detected in D. officinale grown in 2014 and antimicrobials, including carbendazim, difenoconazole and azoxystrobin, were evident in 61.53% of plants. These three pesticides constitute 72.33% of all the antimicrobials detected. Planting methods affected the levels of pesticides and heavy metals. Trellising in plastic sheds was optimal, Both cadmium (Cd) and lead (Pb) levels were high in treed plants, whereas Cr, As and Cu levels were the highest in potted plants.