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目的探讨复发性腹膜后脂肪肉瘤的临床特点、复发因素及诊治方法。方法回顾性分析哈尔滨医科大学附属第二医院2002—2012年收治的37例腹膜后脂肪肉瘤病人13例22次复发的临床资料。结果复发病例较初发者更容易引发临床症状和侵袭周围组织或脏器,手术完全切除率低;随着复发次数的增加,复发间期逐渐缩短,恶性度增加,生存期明显缩短。结论腹膜后间隙的特殊性和肿瘤形态结构的多样性是导致腹膜后脂肪肉瘤不易被彻底切除和术后复发的重要因素,强调首次完全完整和彻底的切除是防止复发、改善预后的关键。
Objective To investigate the clinical features, recurrent factors and diagnosis and treatment of recurrent retroperitoneal liposarcoma. Methods Retrospective analysis of clinical data of 13 cases of 22 cases of retroperitoneal liposarcoma in the Second Affiliated Hospital of Harbin Medical University from 2002 to 2012 was retrospectively analyzed. Results The recurrent cases were more likely to cause clinical symptoms and invasion of surrounding tissues or organs than the primary ones. The total resection rate was low. With the increase of recurrence frequency, the recurrence interval was shortened, the malignancy was increased and the survival time was significantly shortened. Conclusion The particularity of retroperitoneal space and the diversity of tumor morphology and structure are the important factors that lead to the complete resection and postoperative recurrence of retroperitoneal liposarcoma. It is emphasized that the first complete and complete resection is the key to preventing recurrence and improving prognosis.