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目的:回顾性分析妈富隆辅助宫腔镜下子宫内膜息肉切除术治疗子宫内膜息肉的疗效,以探讨妈富隆对降低伴子宫内膜增生息肉患者术后复发率的作用。方法:收集2010~2012年在吉林大学第一医院、第二医院妇科行宫腔镜检查治疗并经病理检查确诊的子宫内膜息肉患者304例,均伴子宫内膜增生(单纯性增生或复杂性增生),所有患者均行宫腔镜子宫内膜息肉电切术及诊刮术;随机分为观察组142例术后第5日开始给予妈富隆口服,治疗3个周期,对照组162例术后不给予任何药物治疗。术后随访1年,观察两组患者术后复发情况。结果:观察组复发7例,复发率为4.9%;对照组复发54例,复发率为33.3%,两组复发率差异有统计学意义(P<0.05)。结论:宫腔镜电切术联合诊刮术为子宫内膜息肉的首选治疗方法,如伴有子宫内膜增生(单纯性增生或复杂性增生),术后辅助妈富隆周期性口服并定期严密随访,可有效降低其复发率。
Objective: To retrospectively analyze the effect of Marvelon assisted hysteroscopic endometrial polypectomy in the treatment of endometrial polyps to explore the effect of Marvelon on reducing the recurrence rate of patients with endometrial hyperplasia. Methods: A total of 304 patients with endometrial polyps diagnosed by hysteroscopy and gynecological examination of gynecological hospital of the First Hospital and the Second Hospital of Jilin University from 2010 to 2012 were enrolled, all of whom had endometrial hyperplasia (simple hyperplasia or complexity All patients underwent hysteroscopic endometrial polyps resection and curettage; randomly divided into observation group of 142 patients on the 5th from the beginning of Marvelon oral administration, the treatment of three cycles, the control group of 162 patients Do not give any medication. Follow-up 1 year after operation, the recurrence of the two groups were observed. Results: The recurrence rate was 4.9% in observation group and 54 cases in control group. The recurrence rate was 33.3%. There was significant difference between the two groups (P <0.05). Conclusion: Hysteroscopic combined with curettage is the preferred treatment for endometrial polyps, such as endometrial hyperplasia (simple hyperplasia or complex hyperplasia), postoperative adjuvant Marvulon oral cyclical and regular Follow-up, can effectively reduce the recurrence rate.