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目的了解上海浦东新区流动人口妊娠期梅毒的筛查情况并分析治疗后的母儿妊娠结局。方法对2008年至2013年在浦东新区妇幼保健院产前检查及分娩的孕妇进行梅毒筛查,确诊后予以驱梅治疗;比较流动人口组与户籍人口组两组间的不良妊娠结局,以及流动人口患者中治疗组和未治疗组之间的不良妊娠结局。结果 1 2008年至2013年妊娠期梅毒的总筛查率为98.90%,发病率为0.57%,治疗率为88.43%;2流动人口组与户籍人口组胎窘和新生儿梅毒的发生率比较,差异有统计学意义(P<0.05);早产、新生儿畸形、胎儿宫内生长受限和围生儿死亡的发生率比较,差异无统计学意义(P>0.05);3流动人口妊娠期梅毒治疗组与未治疗组比较,早产、胎窘、新生儿梅毒、胎儿宫内生长受限的发生率显著下降,差异有统计学意义(P<0.05),新生儿畸形和围产儿死亡的发生率比较,无显著性差异(P>0.05)。结论上海浦东新区流动人口妊娠期梅毒患者的不良妊娠结局发生率高于户籍人口组,积极地驱梅治疗可以显著降低不良妊娠结局的发生率,提高外来流动人口妊娠期梅毒的筛查率及治疗率对改善其妊娠结局有着重要的意义。
Objective To understand the screening of gestational syphilis in floating population in Shanghai Pudong New Area and to analyze the pregnant outcome after treatment. Methods Pregnant women in prenatal care and childbirth in Pudong New District MCH from 2008 to 2013 were screened for syphilis. After diagnosed, they were treated with plum blossom. The adverse pregnancy outcomes were compared between the two groups, floating population and household population Adverse pregnancy outcomes between treated and untreated groups in population patients. Results 1 From 2008 to 2013, the total screening rate of syphilis in pregnancy was 98.90%, the incidence rate was 0.57%, the treatment rate was 88.43%; 2 The incidence of syphilis and neonatal syphilis between the floating population group and the census register population group, (P <0.05). There was no significant difference in the incidence of preterm birth, neonatal malformation, fetal growth restriction and perinatal mortality (P> 0.05) .3 The gestational syphilis Compared with the untreated group, the incidence of preterm birth, fetal distress, neonatal syphilis and fetal intrauterine growth restriction significantly decreased (P <0.05), the incidence of neonatal malformations and perinatal death No significant difference (P> 0.05). Conclusions The incidence of adverse pregnancy outcomes in syphilis during pregnancy in Pudong New Area is higher than that in household population. Positive treatment of flooding can significantly reduce the incidence of adverse pregnancy outcomes and improve the screening rate and treatment of gestational syphilis in floating population Rate to improve their pregnancy outcome is of great significance.